Skip to main content
Premium Trial:

Request an Annual Quote

NHGRI Announces $15 Million for Protein Database Merger

NEW YORK, Oct. 23-The National Human Genome Research Institute today announced a three-year, $15-million grant to integrate the three major international protein sequence databases into a 2-million-protein powerhouse.


The United Protein Database (or UniProt) will combine the two European databases, Swiss-PROT and TrEMBL, with the U.S.-based Protein Information Resource. The project should make data from these three resources easier to access.


UniProt will be divided into two segments: Swiss-PROT will include fully annotated records, as it does now, and TrEMBL will maintain the 700,000 data records that have not yet been hand-curated. The 283,000 entries from the Protein Information Resource will be folded into UniProt.


Swiss-PROT coordinator Rolf Apweiler will be the principal investigator, working with Swiss Institute of Bioinformatics' Amos Bairoch and Georgetown University Medical Center's Cathy Wu, who oversees the Protein Information Resource.


For more information, see the NHGRI statement.

The Scan

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.

Gut Microbiomes Allow Bears to Grow to Similar Sizes Despite Differing Diets

Researchers in Scientific Reports find that the makeup of brown bears' gut microbiomes allows them to reach similar sizes even when feasting on different foods.

Finding Safe Harbor in the Human Genome

In Genome Biology, researchers present a new approach to identify genomic safe harbors where transgenes can be expressed without affecting host cell function.

New Data Point to Nuanced Relationship Between Major Depression, Bipolar Disorder

Lund University researchers in JAMA Psychiatry uncover overlapping genetic liabilities for major depression and bipolar disorder.