The hype around next-gen sequencing is at fever pitch. And while in many ways that's actually deserved with tools that promise to be as revolutionary as these do, it's worth remembering that this technology isn't a good fit for every lab. Though genome centers are amassing fleets of next-gen instruments, some users say that smaller labs might be better off using a service or finding a core facility than investing in the technology themselves.

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In Science this week: International Wheat Genome Sequencing Consortium publishes the bread wheat cultivar Chinese Spring reference genome, and more.

At his FDA Law Blog, Jeffrey Gibbs discusses FDA's technical assistance for the draft Diagnostic Accuracy and Innovation Act.

The New York Times reports that genetic testing has uncovered unfaithful penguins at a Utah aquarium.

Cancer researcher loses funding under new Wellcome Trust anti-bullying policies, the Guardian reports.