Skip to main content
Premium Trial:

Request an Annual Quote

Newcastle University to Use Horizon's X-MAN Models

NEW YORK (GenomeWeb news) – Scientists at Newcastle University will study a panel of Horizon Discovery's mutant and normal X-MAN cancer models for imaging biomarkers that can identify cancer genes within tumors, the university said today.

The goal of the research, which is set to begin this month, is to identify markers that will lead to targeted and personalized drug therapies.

Horizon developed the X-MAN models using its Genesis gene engineering technology.

While recent medical advances have enabled development of targeted therapies for cancer treatment, Newcastle University and Cancer Research UK researcher Herbie Newell said in a statement, "these therapies require tests or biomarkers for effective clinical use in order to match the right drug to the right patient which this collaboration will seek to address."

Financial terms of the agreement were not released.

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.