New Ways To Track Transcripts

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For a while, to peek into a cell's transcripts, researchers mainly relied on microarrays. But with the rise of transcriptomics, the failings of arrays — the biases of using probes, potential for cross-hybridization, and background noise — are thrown into sharp relief as researchers begin to look globally at transcripts and want to have even more information about them. "The big challenge is to map out all the isoforms and go a lot deeper than anyone's ever gone before," says Yale University's Michael Snyder.

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