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A New Role for Viagra?

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A new study published in PNAS is adding to the list of health problems Viagra could be used to treat, says Forbes' David DiSalvo. The study says that sildenafil, the compound sold as Viagra, could be used to treat malignant melanoma as it appears to counteract inflammation caused by a tumor. The researchers gave a group of mice with melanoma Viagra in their drinking water, and found that after seven week, twice as many mice in the treatment group survived compared with untreated control mice, DiSalvo says. "And in the treated mice, T cell counts had returned to normal — indicating that they weren’t being suppressed by the tumor’s inflammatory response — and molecules within the T cells that would typically be deactivated by the tumor’s immune response had also returned to normal," he adds.

The Scan

Study Reveals New Details About Genetics of Major Cause of Female Infertility

Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.

Circulating Tumor DNA Shows Potential as Biomarker in Rare Childhood Cancer

A study in the Journal of Clinical Oncology has found that circulating tumor DNA levels in rhabdomyosarcoma may serve as a biomarker for prognosis.

Study Recommends Cancer Screening for Dogs Beginning Age Seven, Depending on Breed

PetDx researchers report in PLOS One that annual cancer screening for dogs should begin by age seven.

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.