Skip to main content
Premium Trial:

Request an Annual Quote

New Product Watch: Mar 29, 2011

Premium

BlueGnome last week launched a new version of its CytoChip Cancer array for use in high-throughput research applications.

Researchers will now be able to survey eight, 60,000-marker arrays per slide. The initial version of CytoChip Cancer, which was launched in December 2010, provided four, 180,000-marker arrays per slide. BlueGnome's arrays are manufactured by Agilent Technologies.

A BlueGnome spokesperson told BioArray News that the high-density probe coverage of genes important in cancer on the 8x60K format is the same as the 4x180K format. At the same time, the "backbone resolution" across the genome is lower. "The 4x180K has an average spacing of 20 kilobases on the backbone whereas the 8x60K has an average backbone spacing of 60 kb," she said.

The "main difference," she noted, is that the new chips enable users to run eight samples at once, using less sample material and reagents, "making it appealing to high-throughput labs and lowering the cost per sample."


Avantra Biosciences last week introduced its Path protein microarray ultra-thin nitrocellulose slides. The firm claims the substrates provide "very low background fluorescence and excellent signal-to-noise ratio."

Additionally, Avantra claims that the slides offer "excellent" stability, shelf life, and spot morphology. The slides are available in the 1x3 inch "standard slide format" and are adaptable to "all commonly used slide format microarray readers."

Avantra said the Path technology is integrated into its Q400 Biomarker Workstation, which enables researchers to perform multiplex biomarker analysis.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.