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New LightUp Diagnostics Assays Will Include Molecular Probes Technology

NEW YORK, April 10 - LightUp Technologies will launch DNA analysis products, including diagnostic assays, using unique fluorescence-based technology newly licensed from Molecular Probes, the companies said today.


The LightUp probe products can be used to identify and quantify the presence of bacteria, viruses, and other pathogens by detecting and analyzing DNA. Molecular Probes will supply reactive stains that increase sensitivity in detecting DNA and other nucleic acids.


LightUp probe products containing the new technology are expected to launch next month, LightUp said. The product will be an assay that detect and quantifies cytomegalovirus, and will be marketed under the brand name ReSSQ CMV.


"When enhanced with Molecular Probes' fluorescent stains, our LightUp Probes make DNA assays, including those using real-time PCR, even more sensitive, enabling their use in a wide variety of applications in human and veterinary diagnostics, as well as for identifying microbial and viral contaminants, including potential biowarfare agents," said LightUp CEO Ulrica Sehlstedt.


LightUp probes are short peptide nucleic-acid conjugates that increase in fluorescence when hybridized to target sequences. The technology is useful for identifying and quantifying relatively abundant targets in one-step homogenous hybridization assay, according to the company. The probes can be used on their own or in combination with PCR, and can be monitored in real-time or in an endpoint assay.

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