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New Lab & IT Products for Integrated Biology: Oct 1, 2005

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Automation/Robotics

Biomek Automated Tube Bar Code Reader

The Biomek Automated Tube Bar Code Reader allows the processing of open-top, tube-based samples and controls. Integrated with Beckman Coulter’s Biomek Software, the ATBCR establishes positive ID and transfers all data sets associated with a tube or plate during pipetting. It collects data sets during tube-to-plate reformatting, tube-to-tube aliquot sampling, or accessioning. Ideal applications include ELISA plate processing and backup sample storage in environments such as secondary screening, preclinical development, and Phase I and II clinical trials.

Beckman Coulter

www.beckmancoulter.com


Bioimaging

Kodak Image Station In-Vivo F and FX Systems

The Kodak Image Station In-Vivo F and FX systems feature cooled CCD camera technology and selectable multi-wavelength illumination for sensitive, quantitative imaging of luminescent, fluorescent, and radiographic labeled biomolecules in vivo. The system also provides an integrated digital X-ray imaging source and a phosphor-based radiographic imaging screen enabling digital radiography. By precisely co-registering anatomical X-rays of tissues, organs, and whole animals with near-IR, isotopic, or luminescent optical imaging modalities, a significant improvement in anatomical localization of molecular signals is achieved.

Eastman Kodak

http://www.kodak.com/go/molecular


Bioinformatics

Phenyx Web Interface

The latest release of Phenyx, a state-of-the-art protein identification platform, incorporates the Phenyx Web Interface, a new Web-based client used to interact with the Phenyx calculation engine. The PWI introduces a number of new platform features, several of which include: a Protein Details View displaying an extensive interpretation of a specific protein; Excel and XML reports of complete jobs; and a configurable management console that allows users to define their own amino acid modifications and enzymatic cleavage rules and to generate a variety of specific reports.

GeneBio

www.genebio.com


LIMS

OmixLIMS Software Platform for Systems Biology

The OmixLIMS platform is a highly configurable and robust solution aimed at life science and biotechnology laboratories, allowing researchers to manage their lab information, provide sample tracking and experimental workflow capabilities, and ultimately capture, integrate, and manage large volumes of scientific data. OmixLIMS is a scalable solution for managing many diverse research lab environments while providing a unified informatics infrastructure for large research institutes and pharmaceutical/biotechnology companies.

GenoLogics Life Sciences Software

www.genologics.com


Microarrays/gene expression

Agilent Comparative Genomic Hybridization (aCGH) Platform Featuring High-Definition CGH (HD-CGH) Microarrays

Agilent Technologies introduces HD-CGH custom microarrays for pinpointing cancer-related genetic abnormalities. aCGH is one of the most promising methods for identifying and characterizing DNA copy number changes associated with cancer and genetic disorders. Now researchers can easily design their own CGH microarrays to target specific “hot spots” in the genome. Platform enhancements also include reagents and analytics software updates.

Agilent Technologies

www.agilent.com


AlphaScan Microarray Scanner

The AlphaScan microarray scanner is a compact and high-performance slide-based scanner for microarray imaging and data analysis of DNA, protein, cell, and tissue arrays. AlphaScan is optimized for single-slide laser scanning of the commonly used excitation dyes (Cy3, Cy5). It also integrates advanced designs in its optical signal processing and motion control systems, resulting in superior performance capabilities when compared to similar instruments. AlphaScan comes with SpotData Pro software for DNA and protein analysis, and is also available with the ArrayVision software package, licensed from GE Healthcare, to support even more advanced analysis.

Alpha Innotech

www.alphainnotech.com


Nexterion 70mer Oligo Microarraying Kit

The new Nexterion 70mer Oligo Microarraying Kit includes fully optimized microarray slides and reagents for self-spotting, high-quality oligonucleotide microarrays. The slides are coated with an active surface chemistry that is particularly suitable for the covalent immobilization of amino-modified and unmodified oligonucleotides. Benefits of the active chemistry include excellent and reproducible spot size and morphologies, superior signal-to-background ratios, and low non-specific binding. The microarray kit’s individual components cover the most important steps of the microarray process chain: spotting, pre-hybridization, hybridization, and washing.

Schott Nexterion

http://www.schott.com/nexterion


High-Capacity GeneChip Hybridization System

A new carousel for hybridizing 96 Affymetrix GeneChip microarrays is now available. The carousel is designed for reliable, high-speed rotation inside the widely used Model 777 Microarray Oven developed by SciGene. Arrays can be easily inserted and removed from the carousel, yet are held firmly in place during rotation. The system can handle multiple batches of arrays and can support multiple users.

SciGene

www.scigene.com


Proteomics

Finnigan LXQ Linear Ion Trap Mass Spectrometer

The Finnigan LXQ Linear Ion Trap Mass Spectrometer advances high-throughput drug discovery and proteomics by making linear trap performance a cost-effective option for fast-paced analytical laboratories. The Finnigan LXQ offers novel, patented ion trap technology that delivers ultra-fast cycle times and improved ion statistics, resulting in dramatically superior sensitivity and speed over 3D ion traps.

Thermo Electron

www.thermo.com/ms


Transcriptomics

TransPlex Whole Transcriptome Amplification (WTA) kit

TransPlex kits convert total RNA into in vitro cDNA libraries of short, overlapping amplimers that faithfully represent the entire transcriptome of any animal, plant, or microorganism. TransPlex shows little gene- or exon-bias for transcripts up to 10 kb in length, even after extensive RNA degradation. TransPlex kits contain proprietary reagents and protocol sufficient for 24 microarray hybridizations. The protocol is much faster, more reproducible, and less labor intensive than alternative RNA amplification methods, and is scaleable from single tubes to 384-well plates.

Rubicon Genomics

www.rubicongenomics.com


DuraScribe Transcription Kits

The DuraScribe T7 & SP6 Transcription Kits produce RNA transcripts (DuraScript RNA) that are completely resistant to RNase A. The DuraScribe T7 & SP6 RNA polymerases, provided in the kits, are mutant forms of T7 and SP6 RNA polymerases that recognize the same transcription promoters as standard T7 & SP6 RNA polymerase and efficiently incorporate 2’-Fluorine-CTP and 2’-Fluorine-UTP as well as ATP and GTP into full-length DuraScript transcripts.

Epicentre Biotechnologies

www.EpiBio.com


Sample Prep

PickPen Purification Technology

PickPen magnetic particle nucleic acid and protein purification technology streamlines target molecule capture and waste solution removal between processing steps and enhances purity and recovery over traditional purification methods. The pen-like magnetic device is available with a single magnetic tip, with eight-tip multi-sample processing capability, and as a robotic workstation. The PickPen is fully supported with reagents and kits for a wide range of applications, including plasmid and genomic DNA purification, mRNA isolation ranging from the nano- to midi-scale, histidine- and GST-tagged protein purification, protein A and G antibody capture,and streptavidin-based purification.

Sunrise Science Products

www.sunrisescience.com


NUNC CC3 Plates for Cell-Based Screening

NUNC 96-well and 384-well CC3 plates are ideal for colorimetric, fluorescent, or luminescent assays. Solid clear, black with a clear polymer base, or white with a clear polymer base CC3 plates are designed with an ANSI standard footprint for use with robotics and automated systems.

NUNC

www.nuncbrand.com


DyLight Fluorescent Protein Molecular Weight Markers

DyLight Fluorescent Protein Molecular Weight Markers from Pierce are the only markers available that allow flexible one- or two-color fluorescent detection with common imaging systems. Each of the nine proteins is labeled with the DyLight 547 Fluor, which replaces Cy3 Fluor, and the DyLight 647 Fluor, which replaces the Cy5 Fluor. The proteins provide a molecular weight range of 6 K-200 K. The markers are optimized for direct visualization of marker proteins after sodium dodecyl sulfate-polyacrylamide gel electrophoresis and are compatible with Western blotting. They also can be detected by virtually any gel-staining method.

Pierce

www.piercenet.com

 

To tell GT about recently released products, e-mail [email protected]

 

The Scan

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For Martian Fuel

Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo.

To Boost Rapid Testing

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PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing

In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.