NEW YORK (GenomeWeb News) – Using a revamped fluorescent in situ hybridization-based approach, researchers from the University of Pennsylvania were able to detect and quantify single-nucleotide variants in RNA transcripts in both populations of cells and in single cells. As they reported in Nature Methods yesterday, they also used their technique to distinguish between transcripts from maternally and paternally inherited chromosomes.

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In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.