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With New Center, Pall Rides Biotech Wave in India

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In May, Pall opened a 20,000-square-foot process proteomics center in Bangalore, India, a reflection both of the exploding life science and biotech market in the region and the company’s accelerating protein-purification business.

East Hills, NY-based Pall has two other facilities in India, including its Indian headquarters in Mumbai. The Life Sciences Center of Excellence is the third such center Pall created. The company also has a similarly sized center in Cergy, France, for protein purification, and a 4,000-square-foot facility in Woburn, Mass., for protein purification and cellular therapy.

The Bangalore center is equipped with a Surface Enhancement Laser Desorption/Ionization mass spectrometer, a MALDI-TOF mass spec, chromatography systems, and columns.

It is manned by about 60 scientists, who will be conducting research primarily for drug and biotechnology firms. The center also plans to work collaboratively with academic institutions, says Ken Harris, the president of the biosciences division at Pall.

About 7,000 square feet of the center will be devoted to protein purification and customer training, the company says. The same amount of space will be used for pharmaceutical and biotherapeutic validation work, with the rest of the space used for administrative, and sales, and marketing operations.

Harris says that India remains an area with explosive growth potential, reiterating the sentiment of other companies with proteomics businesses that have reported double-digit growth in both India and China, and that have responded by increasing their presence in those regions.

For instance, in India, Thermo Fisher Scientific opened a customer demonstration laboratory in Mumbai, in November 2005, equipped with mass spectrometers and other instruments.

Additionally, an Agilent spokeswoman says that construction has begun on a new company facility there. A year ago Agilent President and CEO Bill Sullivan said the company planned to spend $25 million in India to build a new campus and expand its work force there.

Tony Fong

Short Reads

According to a new agreement, Phenomenex will market and sell Beckman Coulter’s ProteomeLab IgY-12 in North America and in Europe. This protein-partitioning and depletion product is based on avian-generated antibodies and provides a proteome containing medium- and low-abundance proteins that Phenomenex thinks will be useful to biomarker research.
 
Correlogic Systems and Tokyo-based JEOL, a mass spec maker, have entered into an agreement for research and development to improve clinical mass spectrometry. The two companies have been informally collaborating for more than a year. JEOL also makes NMR instruments and electron optical equipment.

Hong Kong’s Bionoetikos agreed to sell and service Eksigent’s NanoLC HPLC products in Asia. According to the agreement, Bionoetikos will distribute Eksigent’s NanoLC-1D and NanoLC-2D proteomics systems to meet the growing demand in Taiwan, the Philippines, Vietnam, Malaysia, Singapore, Thailand, Laos,
and Cambodia.

Customers who order custom absolute quantification peptides from Sigma-Aldrich will be asked to join the company’s new AQUA Peptide Partnership Program. These peptide sequences will be added to the AQUA Peptide Library, which Sigma hopes will contain hundreds of AQUA peptides. After contributing, customers will then pay partnership prices on their orders.

Patents

US Patent 7,228,238. Algorithmic design of peptides for binding and/or modulation of the functions of receptors and/or other proteins. Inventors: Arnold Mandell, Karen Selz, and Michael Shlesinger. Assignee: Cielo Institute. Issued: June 5, 2007.
This patent claims methods for “synthesizing a peptide or peptide-like molecule to a polypeptide or protein target based on mode-matching each member of a set of peptide constituents of the peptide or peptide-like molecule to peptide constituents of the target polypeptide or protein target.”

US Patent 7,231,301. Method and a system for predicting protein functional site, a method for improving protein function, and a function-modified protein. Inventors: Hirofumi Doi, Hideaki Hiraki, and Akio Kanai. Assignee: Japan Science and Technology. Issued: June 12, 2007.
This patent covers “a method for predicting the functional site of a protein using data of the entire proteins of an organism of which genome data or cDNA data is known,” according to the abstract.

Data Point

21 percent
Agilent Technologies plans to launch an upgraded version of its 6410 triple quadrupole mass spectrometer this August. The instrument’s range will be extended to 2,000 m/z from 1,650 m/z, or by 21 percent.

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