New Biomarkers Predict Response for Velcade | GenomeWeb

Millennium Pharmaceuticals has discovered biomarkers that may identify likely responders to its multiple myeloma drug Velcade, and hopes that additional pharmacogenomic research will help improve outcomes and expand use of the drug into a broader multiple myeloma patient population.

Genomic analyses on tumor samples prospectively collected from previously treated multiple myeloma patients revealed that patients with an increased expression of genes in the NF-kB  and adhesion molecule pathways may be more sensitive to the drug.

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The Wall Street Journal reports that National Institutes of Health Director Francis Collins' response to contamination concerns at the agency might have delayed care.

The final revision of the Common Rule doesn't include the proposed change requiring consent for leftover biospecimens.

The first Reproducibility Project: Cancer Biology papers show mixed results.

In Nature this week: mobile phone-based targeted DNA sequencing, and more.