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Neuro Research by the Numbers

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In keeping with this issue’s brain research theme, Genome Technology went straight to the National Institute of Neurological Disorders and Stroke for grant information. We queried grants awarded by NINDS with the keywords “genome,” “proteome,” and “RNAi” to get a sense of how much of the pie is going toward systems biology-related research.

 

It’s no surprise that integrated biology is playing a major role in neuroscience, which is rapidly becoming a large-scale, team-oriented discipline. For the list below, we chose a sampling of grants that came up in our search to give you a good idea of how much money is going toward certain types of projects and research avenues.

The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.