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NCI, NHGRI Pledge $50M Each for Pilot Cancer Genome Project

NEW YORK, Aug. 1 (GenomeWeb News) - The National Cancer Institute and National Human Genome Research Institute have committed to contribute $50 million each to kick off an effort to collect and analyze all the genetic mutations found in human cancers.


The commitment, which still requires approval from the institutes' scientific advisory boards and councils, comes after an NCI and NHGRI-sponsored workshop held last month to get input from members of the scientific community on how best to achieve the project's goal.


The pilot phase of the effort will "focus on addressing the wide range of challenges in cancer biology and technology that must be met in order to implement a successful large-scale human cancer genome project," according to the National Institutes of Health. "The initial phases also will analyze whether the comprehensive cataloguing of the sequence changes in cancer will prove useful in understanding cancer and lead to new methods of diagnosis and treatment."


Initial work on the pilot project, which is anticipated to take three years, is set to begin in 2006.


Additional information on the cancer genome effort is expected to be available in a forthcoming report from the July workshop, NIH said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.