NEW YORK (GenomeWeb News) – The National Cancer Institute is seeking partners that will support its Cancer Human Biobank (caHUB) and its Genotype-Tissue Expression (GTEx) projects by providing clinically annotated normal human biospecimens to both programs.
NCI has issued a request for proposals to entities that can serve as Tissue Source Sites for these programs through basic ordering agreements, which are used to expedite contracts for supplies or services when the quantities, specific items, and prices are not known when the agreement is made.
CaHUB is an effort to establish a centralized cancer tissue resource, a pathology resource center, and associated infrastructure. The mission is to accelerate biomedical and translational cancer research by ensuring a supply of high quality, highly annotated biospecimens.
GTex is aimed at providing a resource for scientists studying relationships between genetic variation and regulation of gene expression. The project will analyze multiple human tissues from donors who will be characterized for germline genetic variation through dense genotyping.
CaHUB will acquire the tissues for GTex through contracts with organizations such as rapid autopsy programs, organ and tissue transplant programs, surgical tissue procurement programs, and medical examiner programs.