In a request for applications, the NIH said the NCI will fund projects focused on developing technologies suitable for the molecular analysis of cancers and their host environment in support of basic, clinical, and epidemiological research.
Examples of technologies and tools of interest under the RFA are ones for in vitro scanning for and identification of the sites of chromosomal aberrations which reflect inherited aberrations or somatic alterations resulting from aging or oxidation, or exposure to radiation or carcinogens, including those that are suitable for scaling for use across whole genomes, detecting DNA adducts, or detecting rare variants in mixed populations; technologies for detection and characterization of nucleic acid sequences of novel exogenous infectious agents that may be present in human cancer; and technologies to elucidate molecular modifications of macromolecules that may be indicative of and critical to the transformation process, said the NIH.
Letters of intent are due by Jan. 17, 2005; May 17, 2005; and Sept. 18, 2005. Applications are due Feb. 17, 2005; June 17, 2005; and Oct. 18, 2005. Additional information is available here.