NEW YORK, March 2 (GenomeWeb News) - The National Cancer Institute said yesterday that it has created what it calls the "largest open-source database for normal tissue from human organs."
Scientists searching for genes implicated in specific diseases can now use the NCI database as a point of reference because it pinpoints which genes are expressed in many of the body's major organs under normal conditions, without known disease, NCI said.
The database, available here, contains expression profiles for 18,927 genes, obtained from 158 tissue samples. Tissue samples were harvested an average of 11 hours post-mortem from males and females of different ethnic groups, ranging from 3 months to 39 years of age, NCI said.
A study describing the database appears in the March 2005 issue of Genome Research.