MDRNA has appeared on the horizon as another RNAi-focused company hoping to make good on the promise of using RNA interference to develop safe and effective RNA-based therapeutics. As part of a shift in business focus, the 55-person Bothell, Wash.-based company changed its name this summer from Nastech to MDRNA. Run by CEO Michael French, MDRNA's goal is to develop novel compounds and unique drug delivery techniques, aiming to get its lead candidate into phase I clinical trials by the end of 2009.

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The US National Institutes of Health has developed guidelines to gauge whether frail chimpanzees are healthy enough to be moved to a retirement sanctuary.

Osamu Shimomura, who won the 2008 Nobel Prize in Chemistry for his work on green fluorescent protein, has died.

In PLOS this week: analytical approach for finding new genetic associations, analysis of Streptococcus pyogenes-infecting viruses, and more.

Stat News reports that the head of IBM Watson Health is leaving her post.