Targeted cancer drugs have helped many patients live longer and healthier lives, but researchers still aren't sure why some of these drugs work in certain patients and not in others, says Technology Review's Emily Singer. Researchers are starting to learn more about how the drugs work by examining the inner workings of cancer cells, which could enable a new approach to personalized treatment — specific combinations of drugs that would more effectively treat a patient's cancer, Singer adds.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.