NEW YORK (GenomeWeb News) – The Cole Foundation has awarded C$700,000 ($720,000) in new grants to researchers at the University of Montreal and McGill University to fund a range of studies focused on leukemia and lymphoma that affects people under the age of 25, the University of Montreal said Tuesday.
The fellowship grants to 14 young researchers will support genomics and molecular biology-based research aimed at discovering new ways to understand and diagnose these diseases.
"Acute lymphoblastic leukemia, or ALL, is the most frequent cancer in children, accounting for approximately 25 percent of all pediatric tumors," said fellowship recipient and University of Montreal researcher Andrea Alter, in a statement.
"Using next-generation sequencing technology, we will examine all gene sequences in a well-characterized group of ALL patients to identify leukemia-specific errors in DNA sequences. Subsequently, we will study the impact of these leukemia-specific mutations on disease susceptibility and disease initiation," Alter continued.
Another fellowship recipient at the University of Montreal, Richard Bisaillon, will study the molecular mechanisms involved in functioning and development of acute myeloid leukemias. At McGill University, researcher Sayeh Davoudi at the Goodman Cancer Research Center will study the role of polymerase in the generation of point mutations, and Gabriela Galicia Vazquez will study a eukaryotic initiation factor as a molecular target for lymphoma treatment.