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The Month of Showers and Fools

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In honor of this month’s best holiday — that’s April Fool’s Day, for anyone who might have been thinking about Passover, Easter, or Tax Day (here in the US) — the Genome Technology editors have rounded up headlines that may be appearing in alternate realities right this minute.

As NIH Budget Crunch Worsens, Researchers Say It’s Easier to Raise Funds by Panhandling on Street Corners; Grant Applications Drop Sharply

Eric Lander Runs Out of Friends with Money; Broad Institute Announces Layoffs, Furniture Auction; Budgets are Restricted to Federal Funds

$1,000 Genome Competition Ends Abruptly as Scientists Realize They Were Using Wrong Reagents; Experiments with Correct Reagents Sequence Genomes for Just $2.99

Universities Sue New Parents for Passing Patented Genes on to Offspring; IP Lawyers Advise Parents to Wait Until Patents Expire Before Producing ‘Generics’

Sick of Studying Y Chromosomes to Find Genghis Khan Descendants, One Scientist Shifts Search to Progeny of Margaret Gorman, Inaugural Miss USA

Three Days from Completion of Sorcerer II Expedition, Craig Venter Succumbs to Seasickness, Calls It All Off

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.