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Money for Medicine

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Continuing on Genome Technology's look at translational medicine research for this issue, we checked into funding for this burgeoning area from NIH, where the field is a key part of the agency's roadmap. Last October, NIH launched a new consortium, funded with Clinical and Translational Science Awards and led by the National Center for Research Resources, designed to revolutionize how clinical and translational research takes place.

Twelve academic centers were chosen as the first members of the new consortium; 52 more received planning grants to help them prepare applications to become members in the future. Member institutions will receive approximately $100 million during this first year, and NIH expects that to increase to about $500 million annually by 2012, when the consortium is slated to be running at full scale with some 60 member centers.

Listed below are the 12 inaugural grants, showing PI, institution, name of the center, and award amount. Total grant amount was calculated by tallying several awards made to each investigator under the same center name.

PI
Institute
Award
Center Name

Frank Arnett 
University of Texas Health Science Center
$6,152,074
Center for Clinical and Translational Sciences

Lars Berglund
University of California, Davis
$4,101,855
Center for Clinical and Translational Sciences

Robert Califf
Duke University
$8,400,350
Clinical Translational Science Institute

Barry Coller
Rockefeller University
$6,718,610
Rockefeller University Center for Clinical and Translational Sciences

Garret FitzGerald
University of Pennsylvania
$10,658,226
Institute for Translational Medicine and Therapeutics

Henry Ginsberg
Columbia University Health Sciences
$8,660,074
Irving Institute for Clinical and Translational Research

David Guzick 
University of Rochester
$5,845,570
University of Rochester Clinical and Translational Science Institute

Joseph McCune
University of California, San Francisco
$16,944,297
Clinical and Translational Science Institute

Eric Orwoll
Oregon Health & Science University
$8,568,942
Oregon Clinical and Translational Science Institute

Steven Reis
University of Pittsburgh
$12,004,574
Clinical and Translational Science Institute

Robert Rizza 
Mayo Clinic College of Medicine
$11,168,752
Center for Clinical and Translational Research

Robert Sherwin
Yale University
$9,175,978
Yale Center for Clinical Investigation

The Scan

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.

Study Looks at Parent Uncertainties After Children's Severe Combined Immunodeficiency Diagnoses

A qualitative study in EJHG looks at personal, practical, scientific, and existential uncertainties in parents as their children go through SCID diagnoses, treatment, and post-treatment stages.

Antimicrobial Resistance Study Highlights Key Protein Domains

By screening diverse versions of an outer membrane porin protein in Vibrio cholerae, researchers in PLOS Genetics flagged protein domain regions influencing antimicrobial resistance.

Latent HIV Found in White Blood Cells of Individuals on Long-Term Treatments

Researchers in Nature Microbiology find HIV genetic material in monocyte white blood cells and in macrophages that differentiated from them in individuals on HIV-suppressive treatment.