Molecular Network Points to Possible Treatment Targets for Alzheimer's Disease | GenomeWeb

NEW YORK (GenomeWeb News) – Late-onset Alzheimer's disease is linked to potentially targetable changes to specific pathways and processes in the brain, according to a new molecular network-based analysis of the condition.

An international team led by investigators in the US and Iceland did array-based gene expression profiling on more than 1,600 post-mortem brain samples from 549 individuals with or without late-onset Alzheimer's disease.

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In PNAS this week: genes involved in histone deacetylation in Arabidopsis, effects of pathogenic presenilin-1 mutations, and more.

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