Modification Marathon

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There’s no shortage of scientists delving into studies of post-translational modifications. A new technology called electron transfer dissociation, or ETD, has gotten plenty of attention -- but is it ready for prime time? GT spoke with experts in the field to get their views on the most efficient and effective ways to detect post-translational modifications (PTMs), as well as their take on ETD and other relevant technologies. Following are excerpts of conversations with the PTM pros.

Josh Coon
Assistant professor, chemistry
University of Wisconsin

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