MIT's Kellis Finds Possible Genetic Switch in Dual-Direction DNA | GenomeWeb


While biologists debate the idea that most noncoding RNA serves no real function in the genome, MIT's Manolis Kellis is busy finding function in the most unexpected places. In his latest work, he's located pairs of miRNAs expressed from the same double-stranded DNA that are both functional. "What we've found out now is that, in fact, for some miRNA genes, the antisense transcript gets processed into a mature miRNA, which itself has distinct functions," Kellis says. "Both directions of the DNA are coding for distinct functions."

Get the full story with
GenomeWeb Premium

Only $95 for the
first 90 days*

A trial upgrade to GenomeWeb Premium gives you full site access, interest-based email alerts, access to archives, and more. Never miss another important industry story.

Try GenomeWeb Premium now.

Already a GenomeWeb Premium member? Login Now.
Or, See if your institution qualifies for premium access.

*Before your trial expires, we’ll put together a custom quote with your long-term premium options.

Not ready for premium?

Register for Free Content
You can still register for access to our free content.

Kuwait says it will alter its law requiring citizens and visitors to provide DNA samples, New Scientist reports.

In Science this week: convergent evolution in bird hemoglobin, and more.

The Wall Street Journal speaks with patients affected by questionable test results from Theranos.

Researchers link variants in TACR3 to hot flashes during menopause, Live Science reports.