Skip to main content
Premium Trial:

Request an Annual Quote

Mediomics Nets $970K SBIR Grant to Develop Protein Screening Tech

NEW YORK (GenomeWeb) – Mediomics has received a $970,000 Small Business Innovation Research grant from the National Cancer Institute to develop a panel of single-chain variable fragments to detect modified proteins, the company said Friday.

The Phase II grant will fund Mediomics' efforts to use its Pincer platform to develop methods to screen for high-affinity monoclonal antibodies that can detect post-translation modification of proteins.

The St. Louis-based company provides assay kits, biosensors, and multiplexed assays for research use, point-of-care testing, and food and pharmaceutical production. The kits will be used to quantify macromolecules, including ligands, proteins, protein complexes, and a range of pathogens. The firm's homogenous assays have already been adapted for the detection of cAMP, tryptophan, S-adenosyl methionine, PDE, biotin, human insulin, and others.

In 2012, Mediomics received a $1 million SBIR grant from NCI to develop a bioanalyzer to detect the titer of protein drugs during their production, and a $740,000 SBIR grant from the Centers for Disease Control and Prevention to develop assays to detect HCV infection .

The company licensed its core technologies, including the Pincer-based bioassay platforms and devices, from St. Louis University.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.