Skip to main content
Premium Trial:

Request an Annual Quote

Medco, FDA to Study Impact of Genetic Testing on Rx Efficacy

NEW YORK (GenomeWeb News) – Pharmacy benefits manager Medco Health Solutions said Monday that it has partnered with the US Food and Drug Administration to study the impact of genetic testing on the efficacy of prescription drugs.
The Franklin Lakes, NJ-based firm said that it would work with the FDA to jointly develop research projects, programs, and strategies in pharmacogenomics.
The agreement runs through the end of August 2010. During the collaboration, Medco will deliver a series of reports to the FDA related to pharmacogenomics, including the safety of prescription drugs, physician participation in pharmacogenomics testing, the usefulness of tests in prescribing, and quantifying prescription information about drugs that have genetic information in their labels.
Medco also said that it will study whether physicians are willing to change a dose of a drug based on a genetic test result. The PBM will use its database of pharmacy claims to “supply a large portion of the data to be used in the reports for the FDA,” it said in a statement.
“Medco’s partnership with the FDA should help establish gene testing as a tool to help lower health care costs and improve the quality of care,” said Medco’s Chief Medical Officer Robert Epstein.
Medco is currently collaborating with the Mayo Clinic on a study of genetic testing in conjunction with warfarin administration and with LabCorp on a study of breast cancer patients using tamoxifen.

The Scan

Sick Newborns Selected for WGS With Automated Pipeline

Researchers successfully prioritized infants with potential Mendelian conditions for whole-genome sequencing or rapid whole-genome sequencing, as they report in Genome Medicine.

Acne-Linked Loci Found Through GWAS Meta-Analysis

Researchers in the European Journal of Human Genetics find new and known acne vulgaris risk loci with a genome-wide association study and meta-analysis, highlighting hair follicle- and metabolic disease-related genes.

Retina Cell Loss Reversed by Prime Editing in Mouse Model of Retinitis Pigmentosa

A team from China turns to prime editing to correct a retinitis pigmentosa-causing mutation in the PDE6b gene in a mouse model of the progressive photoreceptor loss condition in the Journal of Experimental Medicine.

CRISPR Screens Reveal Heart Attack-Linked Gene

Researchers in PLOS Genetics have used CRISPR screens to home in on variants associated with coronary artery disease that affect vascular endothelial function.