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McGill University Sequences Genomeof Antibiotic-Resistant C. Difficile

NEW YORK, Dec. 14 (GenomeWeb News) - McGill University researchers and partners successfully sequenced the genome of a virulent strain of Clostridium difficile, the university said today.


The strain, also known as C. difficile, is a microbe that can cause an infection of the bowel and has been prevalent in Quebec since 2003. Similar to strains found elsewhere in the world, it is resistant to a group of antibiotics called fluoroquinolones. This is the second time worldwide that a strain of this microbe has been sequenced.


Funding for the project came from a variety of sources: Genome Quebec and Genome Canada, the Lady Davis Institute for Medical Research and the Jewish General Hospital Foundation.


McGill researchers, with scientists from Genome Quebec Innovation Centre, MUHC, and Jewish General Hospital, used the ultra high-throughput sequencing technology at the Genome Sequencing Center at the Washington University School of Medicine.

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