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Mayo Clinic Wins $10.2M NIH Grant to Study Pharmacogenomics of Smallpox

NEW YORK, Oct. 5 (GenomeWeb News) - The National Institute of Allergy and Infectious Disease at the National Institutes of Health has awarded the Mayo Clinic a $10.2 million federal contract to study genetic susceptibility to smallpox and genomic-based risks to the smallpox vaccine, the Mayo Clinic said yesterday.


The contract, which will pay out over five years, supports the establishment and operation of a Population Genetics Analysis Program at the Mayo Clinic. Greg Poland, head of Mayo's Vaccine Research Group, will lead the research project, which will study immune-response SNPs that affect an individual's susceptibility to infection, as well as their response to vaccination. The researchers will also study cellular and hormonal responses to vaccination.


The Mayo Genotyping Share Resource, led by co-investigator Julie Cunningham, will perform the genotyping work, while Mayo biostatisticians and members of the Mayo Advanced Genomics Technology Center will provide informatics support.

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