Scientists will miss the complete genome picture if they continue to use the old standby tools for annotation and finding protein-coding genes, according to Akhilesh Pandey. “As a community, we need to remind ourselves time and again that the problem is not solved, and we must use alternative methods,” says Pandey, an assistant professor at the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.