HEIDELBERG, Germany — A pioneer in the field of in silico modeling of biological systems, Masaru Tomita built the first computational model of a single-cell organism — Mycoplasma genitalium — in 1997. But according to Tomita, director of the E-Cell project at the Institute for Advanced Biosciences at Japan’s Keio University, “the major bottleneck [in cellular modeling] is not CPU power, but the lack of quantitative data, especially metabolic data.”

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