Lumera and HMS will develop a silicon chip substrate that combines Lumera's NanoCapture technology with HMS's NAPPA (nucleic acid programmable protein array) technology to create high-density protein arrays with 10,000 spots.
The 10,000-spot array "is a very important step towards our ultimate goal of producing a whole-proteome biochip," said Joshua LaBaer, director of the Harvard Institute of Proteomics, in a statement.
According to Lumera, current protein arrays are limited to around 800 spots.
The NAPPA technology, first published in the July 2004 issue of Science, starts with a printed cDNA array and generates a self-assembled protein array using a cell-free expression mix to produce proteins from the printed genes.
HMS and Lumera will share rights to jointly developed intellectual property.
Further financial details were not disclosed.