Lorus Therapeutics reported the publication of preclinical data on its lead siRNA cancer drug, siRNA-1284, marking the first formal announcement of the company’s intention to play in the RNAi-based drugs arena.

According to Jeff Lightfoot, project manager at Lorus, the company has been working on expanding beyond antisense into RNAi for about three years, primarily focusing on molecules that target R2, a subunit of the enzyme ribonucleotide reductase, which is required for DNA synthesis and repair.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.