NEW YORK, Dec. 3 (GenomeWeb News) - Lexicon Genetics said today it was issued a patent for its gene targeting knockout mouse technology, US Patent No. 6,653, 113.
The patent, issued Nov. 25, is entitled "High efficiency gene targeting in mouse embryonic stem cells." It provides methods for changing the genome of an animal cell through construction of a "targeting" DNA molecule with the desired mutations, then introducing this targeting DNA into a cell in order to induce homologous recombination of the cell's genome. Cells in which this modification has been successfully introduced are then selected.
The Woodlands, Texas-based company said this patent is the seventh it holds in the area of gene targeting.