Skip to main content
Premium Trial:

Request an Annual Quote

Lexicon Genetics Finds New Oncogene

NEW YORK, April 23-Lexicon Genetics said today that it has discovered and validated a previously undescribed oncogene.


The gene, which produces a kinase enzyme, seems to be involved in solid tumor cancers. Overexpression of the gene in mice caused tumor formation, and blocking the enzyme target decreased cell growth and proliferation.


Lexicon intends to identify compounds to inhibit the enzyme target within a year.


Kinases are of interest in oncology research because of their role in intracellular signaling, and the promise that they may provide a key to nontoxic cancer drugs.


Lexicon Genetics, based in The Woodlands, Texas, is publicly owned. The company uses knockout technology to discover gene function.

The Scan

Dropped Charges

The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal.

More Kids

The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children.

PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS

In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more.

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.