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Lexicon Finds New Obesity Drug Target

NEW YORK, June 10-Lexicon Genetics said today that it had identified and validated in vivo a new target for obesity treatments.

 

Researchers at Lexicon created a knockout mouse that was lacking a previously uncharacterized G-protein coupled receptor gene, LG747. These mice accumulated twice as much body fat as normal rodents, leading to an average 35 percent weight increase.

 

Lexicon plans to develop drugs that activate this receptor, in the hopes of finding treatments that reduce body fat and treat obesity-related disease.

 

For further information, see the company press release.

The Scan

US Booster Eligibility Decision

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Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.