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LBNL Genomics Program Begins Using Biolog Phenotype Microarrays

NEW YORK, April 27 (GenomeWeb News) - Biolog's new Phenotype MicroArray technology has been installed and is being used at Lawrence Berkeley National Laboratory as part of LBNL's Genomes to Life project, the company said today.

 

LBNL researchers will use the technology to understand and characterize phenotypes of bacterial strains, particularly Desulfovibrio vulgaris. The phenotypic data will be compared with comparative genomic and microarray experiments at LBNL in order to rapidly deduce stress response pathways in metal and radionuclide bacteria.

 

According to Biolog, of Hayward, Calif., the Phenotype MicroArrays technology allows scientists to simultaneously test hundred to thousands of traits in bacterial and fungal cells to determine changes in gene expression and the effects of drugs. The company is developing similar arrays using mammalian cell lines.

The Scan

Push Toward Approval

The Wall Street Journal reports the US Food and Drug Administration is under pressure to grant full approval to SARS-CoV-2 vaccines.

Deer Exposure

About 40 percent of deer in a handful of US states carry antibodies to SARS-CoV-2, according to Nature News.

Millions But Not Enough

NPR reports the US is set to send 110 million SARS-CoV-2 vaccine doses abroad, but that billions are needed.

PNAS Papers on CRISPR-Edited Cancer Models, Multiple Sclerosis Neuroinflammation, Parasitic Wasps

In PNAS this week: gene-editing approach for developing cancer models, role of extracellular proteins in multiple sclerosis, and more.