Skip to main content
Premium Trial:

Request an Annual Quote

KTH Human Protein Atlas Project to Use BioSilta's EnBase Media for Secondary Screening


This story originally ran on May 20.

Finnish biotech firm BioSilta said this week that the KTH Royal Institute of Technology Stockholm had adopted the company's newly developed EnBase Flo enzyme release media technology for use in secondary screening of poorly expressing proteins as part of the Swedish Human Protein Atlas project.

Use of EnBase Flo will increase the efficiency of the secondary screening process by allowing the KTH researchers to scale down from a shake-flask culture format to a 96-well microtiter plate format while retaining the same amount and quality of cell mass and recombinant protein production, BioSilta CEO Russell Golson told ProteoMonitor.

EnBase kits allow researchers to precisely regulate the release of nutrients to growing cultures, which, according to the company, allows for the production of up to 50 times more cells and 10 times more recombinant protein than traditional methods.

BioSilta has been working with KTH researchers since earlier this year, testing the technology for use in the Human Protein Atlas project, Golson said.

"KTH is quite a conservative group, and we had to go through more than two rounds to ensure that they were getting the quantitative and qualitative results that they were getting with their traditional methods," he said.

Golson declined to give a precise figure when asked the value of BioSilta's contract with KTH, but he characterized the contract as "significant."

"We're a small company, and this is the first customer who will be routinely using it in this type of screening environment," he said.

The Scan

Quality Improvement Study Compares Molecular Tumor Boards, Central Consensus Recommendations

With 50 simulated cancer cases, researchers in JAMA Network Open compared molecular tumor board recommendations with central consensus plans at a dozen centers in Japan.

Lupus Heterogeneity Highlighted With Single-Cell Transcriptomes

Using single-cell RNA sequencing, researchers in Nature Communications tracked down immune and non-immune cell differences between discoid lupus erythematosus and systemic lupus erythematosus.

Rare Disease Clues Gleaned From Mobile Element Insertions in Exome Sequences

With an approach called MELT, researchers in the European Journal of Human Genetics uncovered mobile element insertions in exomes from 3,232 individuals with or without developmental or neurological abnormalities.

Team Tracks Down Potential Blood Plasma Markers Linked to Heart Failure in Atrial Fibrillation Patients

Researchers in BMC Genomics found 10 differentially expressed proteins or metabolites that marked atrial fibrillation with heart failure cases.