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Researchers led by the National Cancer Institute's Hisataka Kobayashi developed "a rapidly activatable, cancer-selective fluorescence imaging probe" to be sprayed onto suspect tissues, as they report in Science Translational Medicine. The probe is activated by with γ-glutamyltranspeptidase, which is found in cancer cells and not normal tissue. "The hope is that surgeons could apply it during or after a procedure to catch any cancer cells they might have missed," adds Erica Westly at Technology Review.

The Scan

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.

Circulating Tumor DNA Linked to Post-Treatment Relapse in Breast Cancer

Post-treatment detection of circulating tumor DNA may identify breast cancer patients who are more likely to relapse, a new JCO Precision Oncology study finds.

Genetics Influence Level of Depression Tied to Trauma Exposure, Study Finds

Researchers examine the interplay of trauma, genetics, and major depressive disorder in JAMA Psychiatry.

UCLA Team Reports Cost-Effective Liquid Biopsy Approach for Cancer Detection

The researchers report in Nature Communications that their liquid biopsy approach has high specificity in detecting all- and early-stage cancers.