By John S. MacNeil

In bioinformatics hardware as in race cars, there are two types of people: Those who insist on purchasing the Corvette off the shelf, and those who can take an old Chevy Caprice, drop in a turbo-charged V8, and create a high-performance vehicle at half the cost of a brand-new car. In the world of bioinformatics hardware, Yoshiki Yamaguchi and his colleagues at RIKEN’s Genomic Sciences Center in Japan are those who build the hot rods.

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The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.

The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.