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Isis Awarded $6M CDC Grant for Development of Diagnostics for Infectious Disease

NEW YORK, Oct. 7 (GenomeWeb News) - Isis Pharmaceuticals said today it has received a three-year grant of up to $6 million from the US Centers for Disease Control and Prevention to develop an RNA-based diagnostic technology for human and animal infectious diseases as well as biodefense.


This grant goes to the Ibis program, which the Carlsbad, Calif., antisense therapeutics company has created to use the company's knowledge of RNA along with genomics, bioinformatics, and mass-spec based high-throughput screening in the creation of a sensor for biological agents, and to develop small molecule antibacterial and antiviral drugs for treatment of these diseases.


Ibis initially developed the biosensor technology, called Triangulation Identification Genetic Evaluation of biological Risks (TIGER)., with funds from the Defense Advanced Research Projects Agency in October 2001. The CDC grant, the company said, will enable Ibis to apply diagnostic technology for identification of infectious agents such as the SARS coronavirus, West Nile virus, monkeypox virus, or drug-resistant bacteria.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.