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Intelligent Bio-Systems Lands $600K SBIR from NIAID to Develop Sequence-Based HIV Test

NEW YORK (GenomeWeb News) - Intelligent Bio-Systems has received a $600,000, two-year Small Business Innovation Research grant from the National Institute of Allergy and Infectious Disease to develop a DNA-sequencing-based test that would detect and quantify drug-resistant variants of HIV-1, the company said today.
IBS licenses its sequencing-by-synthesis technology through a deal with the Columbia Genome Center at Columbia University. As GenomeWeb News reported in December the company is developing its sequencing platform and expects to launch it commercially sometime in 2008.
Although current methods of drug-resistant genotyping can detect this virus only above 20 percent abundance, IBS’ VP of R&D, Jerzy Olejnik, said the company's sequencing technology can detect the virus at 1 percent or less abundance.
Detecting drug resistance at lower levels could enhance the ability of physicians to plan their treatment regimens, the company said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.