Logo

Integrated Genomics Receives NIH Grant to Study Bioterrorism Pathogens

Oct 11, 2006
NEW YORK (GenomeWeb News) – The National Institutes of Health has awarded an undisclosed research grant to Integrated Genomics, the University of Pittsburgh, and the University of Notre Dame to analyze pathogens and bioterrorism agents, Integrated Genomics said today.
 
The project will target three bacterial bioterrorism agents, including Bacillus anthracis, Yersinia pestis, and Francisella tularensis, and two drug-resistant bacteria, Pseudomonas aeruginosa and Staphylococcus aureus.
 
Integrated Genomics will use its ERGO bioinformatics platform to build metabolic reconstructions based on these organisms’ genomic sequences.
 
The research program aims to identify and validate small-molecule inhibitors against enzyme targets that could serve as leads to new antibiotics.
 
The University of Pittsburgh and Integrated Genomics expect the current project to run through 2011.

Breaking News
The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.