Skip to main content
Premium Trial:

Request an Annual Quote

Icoria to Identify Hepatocyte Biomarkers for ADMET Techologies

NEW YORK, April 19 (GenomeWeb News) - Icoria said today that it will use its metabolomics and gene-expression technology to characterize ADMET Technologies' human adult hepatocytes for predictive toxicology screening.

 

Under the agreement, ADMET will provide Icoria with liver cells from patients with a diversity of medical conditions. Icoria will then use its metabolomics, gene expression, and pathway analysis technologies to develop biological profiles and correlate these with differing sensitivities to various classes of hepatotoxic drugs, the companies said.

 

Icoria will retain the rights to commercial development of any novel diagnostic biomarkers discovered during the research. Further financial details were not disclosed.

 

In March, Icoria announced it was selling its agricultural genomics assets to Monsanto, and would reposition itself to focus on biomarker discovery for diabetes, obesity, and liver injury using its metabolomics, gene-expression profiling, tissue analysis software, and computational assets.

The Scan

Two J&J Doses

Johnson & Johnson says two doses of its SARS-CoV-2 vaccine provides increased protection against symptomatic COVID-19, CNN reports.

Pfizer-BioNTech Vaccine Response in Kids

The Pfizer-BioNTech SARS-CoV-2 vaccine in a lower-dose format appears to generate an immune response among children, according to the Washington Post.

Chicken Changes to Prevent Disease

The Guardian writes that researchers are looking at gene editing chickens to help prevent future pandemics.

PNAS Papers on Siberian Dog Ancestry, Insect Reproduction, Hippocampal Neurogenesis

In PNAS this week: ancestry and admixture among Siberian dogs, hormone role in fruit fly reproduction, and more.