On the Hunt for Biomarkers


Biomarker development, from detection to validation, has become a cornerstone in the field of quantitative proteomics. The ability to decipher the presence of signature peptides as surrogates for low- to mid-abundance proteins indicative of disease states carries enormous inherent potential for cancer diagnostics, prognostics, and therapeutics. Consider the deluge of papers published in the last 12 months suggesting candidate biomarkers: a PubMed search for papers associated with the term "potential biomarker" in 2009 yields more than 7,800 results.

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