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How to Find a Good Collaborator

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For computational biologists, finding solid collaborators on the biology side is key to actually applying their programmatic skills. Most systems biology studies entail both computational prediction, or dry lab, and functional validation, or wet lab, work. “It’s always good to have very close collaborators and to work on very specific problems on the biology side,” Ohler says.

Practicing the art of finding a good collaborator takes some effort. As an instructor in Duke’s PhD program in computational biology, Ohler tries to impart to his students the importance of having a clear connection between wet and dry lab. “What we try to do is to have the students realize that they have to not just sit there and code stuff,” he says. “You really have to think about a specific biological question and a specific problem area where you actually will apply your software to.”

Perfecting your coding skills is often not enough. You have to get the scientific community to understand what you’re working on, and the larger context of it. “Often these things are more how you present yourself to other people,” he says, rather than what you’re actually doing.

The Scan

For Better Odds

Bloomberg reports that a child has been born following polygenic risk score screening as an embryo.

Booster Decision Expected

The New York Times reports the US Food and Drug Administration is expected to authorize a booster dose of the Pfizer-BioNTech SARS-CoV-2 vaccine this week for individuals over 65 or at high risk.

Snipping HIV Out

The Philadelphia Inquirer reports Temple University researchers are to test a gene-editing approach for treating HIV.

PLOS Papers on Cancer Risk Scores, Typhoid Fever in Colombia, Streptococcus Protection

In PLOS this week: application of cancer polygenic risk scores across ancestries, genetic diversity of typhoid fever-causing Salmonella, and more.