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High Throughput Genomics, UCSD Team on Diabetes Gene Studies

NEW YORK (GenomeWeb News) - High Throughput Genomics said today it will collaborate with the University of California, San Diego, to generate arrays from mouse tissue samples and from cell lysates to evaluate genes tied to inflammation and insulin production.
 
Under the agreement, HTG will work with the UCSD Department of Medicine's Division of Endocrinology and Metabolism to study how insulin resistance and inflammation function in diabetes.
 
The agreement also calls for HTG to provide its ArrayPlate lysis-only quantitative Nuclease Protection Assay technology, or qNPA, platform, which the company said allows researchers to test any sample, including fixed tissues, without extraction or target amplification.

The Scan

Study Follows Consequences of Early Confirmatory Trials for Accelerated Approval Indications

Time to traditional approval or withdrawal was shorter when confirmatory trials started prior to accelerated approval, though overall regulatory outcomes remained similar, a JAMA study finds.

Sequencing Study Leads to Vaccine Target in Bacteria Behind Neonatal Meningitis

Researchers eBioMedicine track down potential vaccine targets with transposon sequencing on mutant bacteria causing neonatal meningitis in mouse models of the disease.

Multiple Myeloma Progression Influenced by Immune Microenvironment Expression

Researchers in NPJ Genomic Medicine compare RNA sequencing profiles of 102,207 individual cells in bone marrow samples from 18 individuals with rapid or non-progressing multiple myeloma.

Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says

A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups.