High-Resolution Mass Spec Photo Holds Promise for Heart Disease Treatment | GenomeWeb

With a combination of chemical labeling and mass spectrometry, a team of researchers from Oxford University and Case Western Reserve University's School of Medicine Center for Proteomics and Bioinformatics took the first high-resolution picture of the open state of a potassium ion channel.

The method, which uses a mass spectrometry-based structural imaging technology, has allowed the researchers to comparatively analyze gating mechanisms crucial to heart and nerve function, as well as achieve new insight into G-protein coupled receptors.

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