Skip to main content
Premium Trial:

Request an Annual Quote

HapMap Consortium Gets $3.3M in Additional Cash, Plans to Expand Map

NEW YORK, Feb. 7 (GenomeWeb News) - The International HapMap Consortium has received an additional $3.3 million in public/private support and plans to create an improved version of the map of human genetic variation.

 

When the mapping project was launched in October 2002, the consortium said it planned to complete a map of common patterns of genetic variation by September 2005. A first draft, with one million markers, is expected to be ready by the end of this month-eight months ahead of schedule.

 

The consortium said it now plans to build a HapMap roughly five times denser than the map to be produced under the original plan. The new map will use the genotyping capacity of Perlegen Sciences to test an additional 4.6 million single-nucleotide polymorphisms from publicly available databases, the International HapMap Consortium said.

 

The additional HapMap funding came from the Wellcome Trust, which provided $624,000; Genome Canada/Genome Quebec, which gave $260,000; Bristol-Myers Squibb and Pfizer, which donated $100,000 each; Perlegen Sciences, which is giving at least $1.2 million based on in-kind services; and the National Human Genome Research Institute, which pledged $1 million.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.