Two studies, conducted by investigators at the Broad Institute and Massachusetts General Hospital and published in Nature, have identified multiple genetic risk factors and a non-coding gene variant that play major roles in heart disease. In the first of the two investigations, researchers analyzed GWAS of more than 100,000 individuals and found 95 variations across the human genome that contribute to changes in triglyceride and blood cholesterol levels in Western European, African, and Eastern and Southern Asian populations.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.