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From Grades to Paychecks

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It's human nature to want to know how you stack up against your peers. In school, you compared grades, feeling a twinge of pride when you did better on an exam than your hapless lab partner. Maybe you compared baseball or Pokémon cards with friends to see who had the more desirable ones. Then, when school is finally done, salary becomes the competitive benchmark. To help you see how you're doing compared to that old college friend or that irritating benchmate from graduate school, we surveyed 1,870 people in the field, and asked them about their pay, benefits, and more. And for the first time, we also divvy the numbers up by gender.

We extend our thanks to you for responding to our survey as we wouldn't be able to do this each year without your help.

Elsewhere in this issue, Matthew Dublin writes in his Brute Force column that personalized medicine is facing some unique information technology challenges. Exacerbating the issue of including genomic information in health care IT infrastructure is the need for better interpretation, database interoperability, and electronic health records. However, Matt says, these problems are all being tackled.

Tracy Vence reports on the latest approaches researchers are using to make maps of methylation and other epigenetic marks, and make sense of what those marks mean. And Christie Rizk takes a look at research on the tree of life. She spoke with experts who are using genome sequences and metagenomic information to try to determine how bacteria and archaea evolved.

A correction: In an article appearing in the April issue, GT incorrectly identified Affymetrix's vice president of clinical marketing, Dara Wright, as a male. Wright is female.

Finally, a clarification: Last month's proteomics feature stated that an April 2010 Journal of Proteome Research paper, which identified 217 new proteins in saliva, doubled the amount of known salivary proteins. While that study increased the number of proteins known, that knowledge was actually doubled in an earlier study that found more than 2,300 salivary proteins. GT regrets these errors.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.